WebOct 29, 1996 · Abstract The vacuolar protein aminopeptidase I (API) uses a novel cytoplasm-to-vacuole targeting (Cvt) pathway. Complementation analysis of yeast mutants defective for cytoplasm-to-vacuole protein targeting (cvt) and autophagy (apg) revealed seven overlapping complementation groups between these two sets of mutants. WebDec 29, 1997 · Although both the Cvt and Vid pathways mediate the delivery of specific polypeptides from the cytosol to the vacuole, there are probably only limited similarities …
UniProt
WebThe role of autophagy is introduced, shown to be required for proliferation in the phyllosphere, and selective autophagic pathways such as pexophagy and cytoplasm-to-vacuole targeting (Cvt) pathway are strictly regulated during both the daily cycle and the host plant life cycle. Expand WebDec 1, 2002 · The cytoplasm to vacuole targeting (Cvt) pathway is an autophagy-related trafficking pathway whose cargo proteins, aminopeptidase I and α-mannosidase, are selectively transported from the cytoplasm to the lysosome-like vacuole in yeast. This study elucidates a molecular mechanism for cargo specificity in this pathway involving … lawn mowing near me one time
Structural Biology of the Cvt Pathway - PubMed
WebMay 1, 2007 · The Cytoplasm-to-vacuole targeting pathway (Cvt) in S. cerevisiae is the best understood mode of selective autophagy. It has so far only been found in yeast, … WebJan 1, 2013 · Atg1 is a key Atg protein, as it is required for both nonselective and selective autophagy such as the cytoplasm-to-vacuole targeting (Cvt) pathway. In the Cvt pathway, the substrates prApe1 (precursor of aminopeptidase) and Ams1 (α-mannosidase) form homo-oligomers in the cytoplasm and are then enwrapped by the autophagosomal … Webthe cytoplasm to vacuole targeting (Cvt) pathway, that were isolated because of de-fects in proteolytic processing of the resident vacuolar hydrolase aminopeptidase I (9–11). The overlap between the apg, aut, and cvt mutants was surprising, because the respec-tive pathways, autophagy and Cvt, operate under distinct conditions. Autophagy is pri- lawnmowing next door