Web6 Apr 2024 · Smooth muscle cell (SMC) is a key component in neointimal hyperplasia in venous stenosis [6, 7]. Apart from venous stenosis, another cause of access failure is an initial failure to mature [ 4 ], arising from inadequate smooth muscle generation to facilitate venous wall thickening [ 8 ]. WebKey Words: smooth muscle cell n apoptosis n cell death n phospholipids O xidation of LDL lipids in the arterial wall is believed to play a key role in the formation of atherosclerotic le-sions.1–3 Oxidized LDL particles are removed by macrophages via scavenger receptors, resulting in the formation of foam cells.
Proliferative, degradative smooth muscle cells promote aortic …
WebA smooth muscle cell is a spindle-shaped myocyte with a wide middle and tapering ends, and a single nucleus. Like striated muscle, smooth muscle can tense and relax. In the relaxed state, each cell is 30–200 micrometers … WebCSC increased the expression of inflammatory markers and reduced the contractile ones in both cell types, with KLF4 modulating the SMC phenotypic switch. Next, we performed a mass spectrometry-based differential proteomic approach on human SMCs and could show 11 proteins were significantly affected by exposition to CSC (FC ≥ 2.7, p ≤ 0.05). kinshicho restaurants
Epigenetic control of vascular smooth muscle cell lineage …
Web8 Nov 2024 · Introduction: Vascular smooth muscle cell (SMC) phenotypic switch from a contractile to a synthetic phenotype plays a significant role in vascular pathologies, including atherosclerosis, restenosis, and aneurysm. Latexin (LXN) is a novel inflammatory protein that is highly expressed in SMCs; the role of LXN in SMCs biology, however, remains … WebThis is in distinct contrast to the rabbit SAA3 synthesis by neonatal aortic smooth muscle cells (SMC) or by synovial cells in response to IL-1 alone . Human A-SAA was also expressed by synovial cells stimulated with a combination of Dex and IL-1, not with Dex or IL-1 alone [ … WebSmooth muscle cells orchestrate the endothelial cell response to flow and injury. Circulation. 2010 May 25;121(20):2192-9. doi: 10.1161/CIRCULATIONAHA.109.877282. … lyndon pick